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KMID : 0364219830260010001
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Korean Journal of Zoology
1983 Volume.26 No. 1 p.1 ~ p.17
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Synthesis of Muscle-Specific Proteins During the Differentiation of Chick Embryonic Muscle Cells in Culture
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Ha Doo-Bong
Yoo Byoung-Je
Sonn Jong-Kyung
Kang Ho-Sung
Lee Young-Sub
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Abstract
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The synthesis of myosin, actin, tropomyosin and troponin in the cultured muscle cells of chick embryo during the differentiation were analyzed. The synthesis of myosin and actin were very active prior to the myoblast fusion while the troponin synthesis became active after the fusion. Tropomyosin was synthesized practically constantly throughout the culture period. Several proteins were detected in the muscle-conditioned medium strongly suggesting that the cells in culture released polypeptides which might act on the membrane of neighboring cells cells to initiate the fusion.
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